Author(s):
1. Dijana Đeorđić, Fizički fakultet, Serbia
2. Marija Perović, Serbia
3. Marko Bošković, University of Belgrade, Vinča Institute of Nuclear Sciences, Serbia, Serbia
4. Erzsébet Illés, University of Belgrade, Vinča Institute of Nuclear Sciences, Serbia, Serbia
Abstract:
The use of magnetic nanoparticles provides a novel strategy for improving tumor treatment. The temperature increase is prodused by applying an alternating magnetic field to a magnetic nanoparticles. High temperatures can damage and kill cancer cells, usually with minimal injury to normal tissues. The thermal treatment at elevated temperature is called hyperthermia. Presented expperimental research was focused on obtaining iron oxide nanoparticles with high efficiency for magnetic hyperthermia treatments. They were prepared by two different synthesis methods.The first sample was prepared in the modified process of thermal decomposition of Fe precursor in a polyol solution. The second sample was prepared by coprecipitation based on mixing iron salts solution with NaOH solution. Samples were characterized by X-ray powder diffraction, transmission electron microscopy, SQUID magnetometry and Zetasizer Nano series. The results derived on two systems obtained by different synthesis methods represent valuable knowledge in the fundamental research on magnetic behavior of nanoparticles systems, but also significant contribution in the developing field of application of magnetic hyperthermia.
Key words:
magnetic nanoparticles,iron oxide,hyperthermia,cancer treatment
Thematic field:
SYMPOSIUM B - Biomaterials and nanomedicine
Date of abstract submission:
11.06.2017.
Conference:
Contemporary Materials 2017 - Savremeni Materijali